Tuesday 2 April 2019
Monday 1 April 2019
Friday 14 December 2018
Knowing The Science Behind Your Athletes Supplements At FX Supplements
Knowing The Science Behind Your Athletes Supplements At FX Supplements
Being properly informed and educated on sports nutrition and supplement usage is extremely important here at FX. We are deeply committed to and passionate about the science and athlete/coach education of our product range.
Pictured Below – FX Supplements Client Sadam Kuomi British National 400 metre Champion
The team at FX supplements are fully qualified nutritionists who source the best performance brands available across the globe, that’s why we’ve partnered with several ethical companies and medical experts to ensure our coaches, trainers, health professionals and athletes have access to the latest knowledge in order to optimize their performance, nutritional status and usage of our products.
Our high strength products are all
“practitioner only” and specifically created to meet the growing demands of athletes and health enthusiasts to ensure you are at your best year round.
Most of our supplement ranges are made or formulated by medical doctors such as 42 time full Ironman finisher Dr. David Minkoff of Body Health USA.
Also the medical team at Hifas Da Terra head quarters in Pontevedra, Santiago, who we spent time with in Spain this year to analyze our on-going studies and data that our performance Nutritionist Lee Compton has been working on with his national & international athletes on Cordysin Sports (Cordyceps) We spent time with Dr. Esteban Sinde Stompel Phd Biology, Dr Fernandez De Ana Magan PHD & company director Catalina De Ana. We look forward sharing these studies and data which are due to complete in the coming months.
Our probiotic range NDS Probiotic (Nutrient Delivery System) are each science and evidence based with onsite testing at many leading hospitals across Europe.Also our specific athlete probiotic “NDS performance” has been tested in a randomized double-blind placebo controlled trial at the medical university at Gratz, Austria
Nutri Advanced UK are also a fantastic supplier of high grade practitioner only supplements and offer our regular updates and training for our team on a monthly basis via their product managers at our location in Ireland.
Remember, the content of the supplements you consume is crucial. You must ensure they are utilised by the body as much as possible. Poor quality supplements loaded with binders and fillers result in excess waste that your body must process and remove, with only minimal amounts of the supplement being absorbed and utilised by the body.
Avoid marketing driven fads. Get accurate professional advise on your supplement protocol based on your individual biochemistry. Just because it says supplement doesn’t mean it’s good!!!
Got a question?
FX supplements is the brand you can talk to: Our team are qualified Nutritional therapists and are at the end of our advice line, open to you, for product support and to answer your queries – Team FX
The post Knowing The Science Behind Your Athletes Supplements At FX Supplements appeared first on .
source https://fxsupplements.ie/knowing-the-science-behind-your-athletes-supplements-at-fx-supplements/
Wednesday 12 December 2018
Shaping You Infants Gut Bacteria For Life – FX
Did you know, predominately babies who are born via vaginal delivery have a diverse range of bifidobacteria transferred orally during delivery and seeding their immature guts and shaping their digestive ability and immune system for life. Recent research is outlining that the number of bifidobacteria is declining and setting up an environment that is promoting chronic disease including food sensitivities & allergies, diabetes, asthma, eczema and obesity later in life.
NDS Panda 1 product was designed with this in mind providing a range of bifidobacteria for the infant right up to 12 months to promote optimum gut bacteria. This is suitable from birth. This product is used by mums whose babies are born vaginally to enhance diversity and in many cases by moms whose babies are born via c section as this has been high lighted as one of the areas contributing to bifidobacteria decline. Babies born via c section have been found to possess quite an altered gut bacteria diversity as they are missing this vital seeding process that happens with vaginal delivery.
Panda 1 may help:
Shaping an infants gut bacteria
Promoting a healthy immune system
Enhancing digestion and absorption of nutrients
Reducing digestive complains including colic
See full details of through the link below
The post Shaping You Infants Gut Bacteria For Life – FX appeared first on .
source https://fxsupplements.ie/shaping-you-infants-gut-bacteria-for-life-fx/
Friday 17 August 2018
The Benefits Of Bi-Annual Probiotic ‘s & Why We Choose NDS Probiotics At FX Supplements
The Benefits Of Bi-Annual Probiotic ‘s & Why We Choose NDS Probiotics
Because our western environment leaves us deficient in bacterial exposure its well recomended and documented to feed out gut with bacteria by supplementing bi-annually with specific strain proboitics.By providing your gut bacteria the healthist environment possible will allow the healthiest bacteria to grow. We recomend you create a optimum environment for you and your children’s ecosystem through an individualised approch.
About NDS Proboitics
NDS have been in the health food business since 1984 and are the leading supplier of evidence based multistrain probiotic in powder and all our probiotic formulas are based on scientific research and are well documented, effective and safe. Their aim is to only use ingredients that are as close to nature as possible. We supply to professionals across Europe & United Kingdom and now Ireland through our Irish partner and leading Natural health clinics Nadura – Integrative Natural Health Ltd. Our products do not contain any chemicals, colourings, preservatives, additives or flavourings.
Basics of NDS Probiotics
NDS® Probiotic contains several different and specially selected good intestinal bacteria in freeze-dried form. This means that the bacteria have been dried and pulverised after the freezing process. The liquid required in their active form has thereby been removed from the bacteria.
Most products containing intestinal bacteria undergo this process. Before ingestion, NDS® Probiotic must be dissolved in lukewarm water and left for 10-15 minutes before drinking. The most effective method is to drink the mixture before bedtime or some time before breakfast.
The reason for NDS® Probiotic having to be dissolved in water before ingestion is that the bacteria must be given time to absorb the water required for their reactivation and efficient ability to function. They must be rehydrated in clean water and not in drinks such as milk, squash or fizzy drinks. When capsules or tablets are ingested, they initially arrive in the stomach with its acidic environment and other liquids. This is a tough ride for dry bacteria that quickly need to absorb liquid to become active again
To aid the bacteria further in handling the osmotic shock involved in suddenly being exposed to liquid, the manufacturer of NDS® Probiotic has added special nutrients to the bacterial mixture. These include three different minerals and some prebiotics (food for probiotics). This improvement gives the bacteria a ‘packed lunch’ for their journey through the gastrointestinal tract to increase their chance of growing and attaching to the mucous membrane of the gut.
Due to these added nutrients, NDS® Probiotic has at least two years’ documented stable shelf life at room temperature.
One measure of bacterial efficiency is that they are able to produce sufficient acid to reduce pH levels efficiently. The lower the pH is during testing, the more efficient the bacteria are. This study compares a competing product called X with NDS®
Both products have the same number of bacteria per gram, in this case 109 = 1,000,000,000 bacteria per gram. During testing over five hours, NDS® Probiotic managed to lower the pH from 5.7 to approx. 4.2. Product X only managed to lower the pH from 5.7 to approx. 5. Based on this study, it can be concluded that the bacteria in NDS® Probiotic are more active and efficient than the bacteria in product X.
The various NDS® Probiotic products contain from 500 million to 10 billion bacteria in a single gram of product. As the standard recommended dose is one teaspoonful that weighs between 3 and 5 grams, a daily dose will contain between 1.5 and 50 billion viable bacteria. Not many competing products are able to match that.
NDS BioActive technology improves the efficacy of the bacteria strains.
BioActive technology is based on research in prebiotic compounds, minerals and enzymes. The BioActive technology consists of bacteria specific protective and nutritional ingredients. These ingredients are specifically selected to increase;
Shelf life
Product stability and longer shelf life. Our technology protects the bacteria in the product against environmental conditions and allow storage at room temperature. Often environmental conditions kills a large number of the bacteria in many products.
Gastro-intestinal survival of the bacteria
Surviving the stomach and gastro-intestinal (GI) tract is the first basic functionality of a probiotic product. The more bacteria that survives the GI-tract, the better the effect. When the bacteria are unprotected a large number of bacteria is killed as a result of the low pH in the stomach and the fluids in the GI-tact.
BioActive technology protects the bacteria against acidic conditions in the stomach and keeps them alive and active.
Activity of the bacteria in the intestine
After survival of the GI-tract, the probiotic bacteria are in the small intestine and to be effective at the right time and at the right place. We have selected ingredients that will bring the bacteria into an active state. BioActive technology provides the bacteria with their nutritional needs. They are able to colonize, resulting in an even more effective probiotic product.
By using this technology NDS has created real symbiotic, highly active probiotic.
NDS Probiotics Individualised Products, Explore the range
NDS® Probiotic S-60 NRG
This product we use with our Performance Athletes or anyone under long-term stress be it from lifestyle, employment or endurance sports in cases of chronic fatigue syndrome or other immunological disorders, autoimmune diseases and the build-up of toxins – as well as in detoxification phases where similar, complicated health problems need to be addressed.NDS® Probiotic S-60 NrG, the strains have also been selected on the basis of avoiding any production of unwanted D-lactic acid.
NDS ® Probiotic Barrier For Leaky Gut
NDS® Probiotic Barrier has been developed in collaboration with Wageningen University and Hospital Gelderse Vallei in Ede, the Netherlands. It is a multispecies probiotic product specifically developed to strengthen and improve the intestinal barrier function. It’s results and scientific data in the area’s of inflammation, Migraine and gut permeiability (Leaky gut)
NDS® Probiotic Classic ® Broad Spectrum Proboitic
NDS® Probiotic Classic® is a multispecies probiotic specifically designed for managing and maintaining the intestinal balance. Since the product is a multispecies broad-spectrum formulation, it is able to be active at all three different levels
- Inhibit various pathogens such as C. difficile, E. coli, E. faecalis.
- Improve barrier function
- Influence the immune system
NDS® Probiotic Performance can improve intestinal barrier function, low-grade inflammation and redox homeostasis.
NDS® Performance Athlete Probiotic has been tested in a randomized, double-blind, placebo-controlled trial at the Medical University of Graz, Austria. Twenty-three endurance sportsmen received a daily dose (1*1010 cfu/day) of NDS® Probiotic Performance or placebo for 14 weeks.
The triple step test ergometry was used as a model for stress. This performance test to measure maximum endurance capacity was performed at baseline and at the end of the treatment. Markers for intestinal barrier function, oxidative stress and inflammation were measured. The trial showed that supplementation with NDS® Probiotic Performance significantly decreased stool zonulin levels, an important marker for a ‘leaky gut’. Moreover, a trend was shown towards a decrease in the chronic inflammatory marker TNF-α.
NDS® Probiolax® for constipation and sluggish bowel in people of all ages (children + 1 y old).
Constipation is characterised by the following criteria:
–infrequent defecation, less than three times per week
–faecal incontinence (dirty underwear), more than two times per week, only seen in children with constipation
–passage of large and painful stools –retentive posturing
Constipation is the most common gastrointestinal disorder affecting between 12-27% of the general population. Great to know it’s not just you isn’t it?
There are many factors that directly affect our bowel transit time some including diet and hydration levels, however research is now pointing to probiotics and gut bacteria levels playing an essential role. Constipation sometimes becomes part of peoples everyday life, because it’s not an acute illness or disorder it tends to be ‘tolerated’ by individuals but can cause an array of symptoms including pain, bloating, cramping, nausea, haemorrhoids and a general uncomfortable sensation that continues to persist. Sometimes despite dietary changes and increasing hydration levels it can persist, this is where our gut bacteria need to be addressed.
So how can bacteria affect my bowel? There are numerous ways! Gut bacteria greatly influence the speed at which our gut pushes our food through our digestive tract (peristalsis), mainly via food digestion but also through electrolyte stimulation which softens our stool making them easier to travel. Bowel movements need to be regular, generally between 1-2 bowel movements daily is optimum for health and transit time. If an individual is chronically constipated not only can it cause the above symptoms, it can also cause more bacteria being reabsorbed back into the hepatic (liver) system which is over time can hinder the livers detoxification capability. Did you know a simple course of anti-biotics can alter our gut flora distribution and quantity which can be enough to induce constipation and a change in bowel patterns?
NDS Probiolax is a multispecies probiotic product, designed with the specific aim to ease away constipation. NDS® Probiolax has been developed in close cooperation with the Children’s Hospital of the Academic Medical Centre (AMC) of the University of Amsterdam. The bacterial strains of NDS Probiolax have been specifically selected for their capacity to – inhibit Clostridium difficile and Staphylococcus aureus and to increase production of lactic acid to improve the motility and peristalsis of the intestine.
Clinical evidence- NDS Probiolax has been tested in a clinical study, organised in collaboration with the Children’s Hospital of the Academic Medical Centre of the University of Amsterdam. Twenty children suffering from constipation used the product for four weeks (once daily). Results showed that NDS Probiolax was able to induce a significant increase in the amount of bowel movements per week, a significant decrease in the amount of abdominal pain and a significant decrease in the amount of faecal incontinence (dirty underwear).
Why ‘tolerate’ constipation and its hindering symptoms when you don’t have to?
For the establishment and maintenance of an intestinal flora that contributes to a healthy metabolism in both children and adults.
NDS® W8 Probiotic For Overweight & Weight Loss
Being overweight is usually defined as a BMI between 25 -30 (kg/m2) while having a BMI > 30 is defined as obesity. In the past 30 years or so, the percentage of people who are overweight has grown significantly. The causal links are complex as many genetic factors and lifestyle components, such as eating habits and the level of physi- cal activity, the balance between energy-giving nutrients, individual metabolism and ability to regulate metabolism, all play a part.
In earlier times and throughout human history, intermittent scarcity of food would occur depending on season, population density, wars and natural disasters, so the people who survived the times of scarcity were those who were particularly good at ‘storing’ when food was plenty. We also know that babies who have been starved as foetuses and are therefore born underweight in relation to the length of the preg- nancy, adjust their ‘biological regulator’ to ‘starvation’ and are therefore coded to utilise food very efficiently so that when they are given sufficient amounts of food, there will be a greater risk that they will become overweight. This is hitting society like a boomerang now, when most societies in the world have access to energy-dense and nutrient-poor food and industrial development is gaining speed and eliminating the need for the physically demanding activity of earlier eras.
Occurrence: the high level of overweight and obese people is noticeable in many countries, independent of geographical location, ethnic composition of the popula- tion, age and gender. Table 1 shows the percentage of people who are overweight (BMI 25-29.9) and obese (BMI +30). The prevalence of both overweight and obesity is high all over the world, and that the only group with a lower prevalence is adults in Asia. This means that there is a serious mismatch between our biological needs and the overall environment that we have created.
NDS® Probiotic Skin Active (Also Available At The Highly Regarded Wexford Skin Clinic)
With the recent launch of the latest innovation in skincare NDS SkinActive® Probiotic, the results are simply outstanding and the science and studies stack up.
For cosmetic reasons, we would like our skin to remain beautiful and supple for as long as possible. And this should preferably be in a natural way so we avoid going under the knife or getting injections. The skin is nourished by the nutrients our diet consists of. You are what you eat, and your skin shows exactly that. New skin cells are formed about every 28th day. A healthy diet and sufficient fluids is the prerequisite for beautiful and strong skin. The skin is a very large organ, as far as its weight is concerned and it has an area of approx. 2 m2. The skin is our barrier between the inner and outer surroundings. It is important to keep this barrier intact.
For example, the skin must protect us against heat, cold, radiation and micro-organisms. The skin also regulates our body temperature and helps to create vitamin D. About 75% of the skin’s dry weight consists of collagen peptides, which is embedded in the skin’s connective tissue. NDS® Probiotic SkinActive® is a new dietary sup- plement product for plump and radiant skin. The product contains collagen peptides, zinc, vitamins E and C combined with four probiotic Bifidobacteria with nutrients for the delivery of these bacteria. The ingredients in NDS® Probiotic SkinActive® nourish the skin’s three layers from the inside and replenishes the skin with the nutrients it needs.
Our Specific Children’s Range Of NDS Proboitics
Children’s NDS Panda 1
This specific range is used in younger children for a full range of different symptoms but also used in the prevention and treatment of allergies in both children and adults. Also for pregnant or breastfeeding women who are worried that their child may develop an allergy.
5 specially selected bacteria strains in a complex of rice starch, maltodextrin, minerals and enzymes. Used by mothers when six months pregnant and for babies during the first 12 months after birth. Well tolerated by those in need of eczema risk reduction.
NDS Panda 2
This specific range is used in younger children for a full range of different symptoms but also used in the prevention and treatment of allergies in both children and adults. Also for pregnant or breastfeeding women who are worried that their child may develop an allergy.
In Europe, probiotic strains are con- sidered safe if they have the Qualified Presumption of Safety (QPS)-status5. All probiotic strains in NDS® Probiotic Performance have the QPS status.
The post The Benefits Of Bi-Annual Probiotic ‘s & Why We Choose NDS Probiotics At FX Supplements appeared first on .
source https://fxsupplements.ie/the-benefits-of-bi-annual-probiotic-s-why-we-choose-nds-probiotics-at-fx-supplements/
Saturday 7 July 2018
Exercise-induced gastrointestinal dysfunction in endurance athletes
Endurance Athletes & Increased Probiotic Needs
If you’re an endurance athlete and frequently experience digestive problems, chronic colds or sub-optimal recovery or getting dropped out the back on race day or Sunday morning? This blog post may be for you?
In clinic we regularly identify increased need for probiotics for endurance athletes as is the nature of endurance sports like cycling, triathlon or tunning, they do tend to attract the more extreme individuals that like to push the body to its limits on a regular basis which does deplete the body of vital nutrients and bacteria that needs to be replenished by everyone, but much more by endurance athletes.
So what are the benefits to probiotics and why do we feel that NDS Probiotic “Performance” are the best available?
They improve recovery by increasing antioxidant absorption, which is paramount post training as free radicals are abundant during this time. it’s important that athletes meet them head-on with high amounts of antioxidant rich food in recovery and throughout each day. When eaten during recovery, probiotics increase antioxidant absorption, and thereby promote extra free radical fighting just when you need it.
Probiotics support immune function by promoting higher levels of the natural virus fighter, interferon, which is decreased in fatigued athletes. Typically endurance athletes are more prone to sickness more often than less-healthy individuals who don’t exercise as much? One area of suppression is the immune system, and specifically interferon’s, which are proteins made and released by cells in response to the presence of pathogens such as viruses, bacteria and parasites. Studies have shown an increase in interferon’s in fatigued athletes with the supplementation of healthy bacteria, and thereby a decrease in illnesses such as mononucleosis.
A healthy bacterium improves digestion by increasing the bioavailability and absorption of proteins and fats. Healthy bacteria can improve the digestion of these nutrients in the stomach and intestines. Athletes have some of the highest nutrient needs of anyone, and these needs are best met when digestion is improved. Also, they can acutely reduce nausea, intestinal inflammation, bloating and hypersensitivity to foods—common complaints among athletes during and after training.
NDS Probiotic Performance
NDS® Probiotic Performance can improve intestinal barrier function, low-grade inflammation and redox homeostasis. Main usage indications: Performance to be used mainly for athletes – to prevent runners diarrhoea and also to prevent increased risk of intestinal permeability that comes with sports
The science
Performance has been tested in a randomized, double-blind, placebo-controlled trial at the Medical University of Graz, Austria. Twenty-three endurance sportsmen received a daily dose (1*1010 cfu/day) of NDS® Probiotic Performance or placebo for 14 weeks.
The triple step test ergometry was used as a model for stress. This performance test to measure maximum endurance capacity was performed at baseline and at the end of the treatment. Markers for intestinal barrier function, oxidative stress and inflammation were measured. The trial showed that supplementation with NDS® Probiotic Performance significantly decreased stool zonulin levels, an important marker for a ‘leaky gut’. Moreover, a trend was shown towards a decrease in the chronic inflammatory marker TNF-α.
When to take a probiotic?
As a performance nutritionist i have typically two different answers, but typically for the average individual I suggest that if you take a probiotic twice per year and eat a balanced prebiotic & probiotic rich diet this should suffice. I recommend to my clients that if you use the “Changing of the clocks” as a reminder bi-annually as this is typically when we would need them most. However if you are an endurance athlete with heavy training load I would recommend you double this dose and take a probiotic every three months.
Should I just take NDS Performance?
No, not always but if your a sports person or athlete then yes this is the product designed for you. With that said NDS are the only company to design products with specific strains for specific illnesses so if you think you or one of your family have a different need don’t hesitate to contact us here at hello@fxsupplements.ie because this range have many other options depending on symptoms. Please see bellow
NDS Barrier – For behaviour issues and leaky gut
NDS ILD – Specifically for IBS (Crohn’s Disease & Ulcerative Colitis)
NDS W8 – Specifically for weight loss
NDS Probiolax – Specifically for constapation
NDS s60 – Specifically for stress or very physically active individuals
NDS Skin Active – Designed for all skin issues
NDS Classic – Designed as a broad spectrum probiotic
NDS Panda 1 & Panda 2 – Children’s range
NDS Performance – Sports specific
If you have a query on what and when you should take probiotics don’t hesitate to contact us here at FX
Team FX
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source https://fxsupplements.ie/exercise-induced-gastrointestinal-dysfunction-in-endurance-athletes/
Saturday 31 March 2018
Perfect Amino “The Science” Understanding Amino Acid Utilisation From FX
As published in an International medical journal in 1998, a comprehensive and conclusive study investigated the most effective pattern of dietary essential amino acids in order to achieve maximum metabolic utilization. This study identified the precise net nitrogen utilization (known here as Amino Acid Utilization or AAU) of various dietary proteins, which measures how much of a protein is actually absorbed and used by the body. This study also established a pattern of the essential amino acids that can be fully utilized for protein synthesis with minimal, nitrogen waste. This ultimately results in maximum efficiency for protein synthesis and reducing the toxic load on the body’s elimination pathways.
The study was a comparative study and determined the percentage of amino acid utilization (also known as net nitrogen utilization. It was conducted on 66 subjects, over a 12-week period, where they were alternately given a specific amino acid formula as compared to amino acid formulas based on other dietary proteins such as eggs.
This study showed a considerable amount of nitrogen waste from the dietary proteins, and confirmed the discovery of a unique pattern of essential amino acids (PA) for human nutrition, capable of inducing an Amino Acid Utilization (AAU) that was extremely effective.
The authors of the study chose a participant group that was comprised of 66 healthy people, half men, half women. Average age was 27 and they were all in good health, between 27 and 40 years old and were not underweight, pregnant or lactating or had chronic diseases. These 33 men and 33 women were randomly arranged into 3 groups of 11 men and 11 women, in groups 1, 2 and 3.
Over the next 114 days, in double-blind conditions, with a triple crossover technique, the subjects were given the various amino acid combinations in different sequences. First, their protein and energy metabolism was equalized and stabilized with a uniform diet to avoid metabolism differences. Then over the next 84 days, their nitrogen balances were assessed and determined.
After carefully monitoring and controlling the nutrition intake and then measuring the nitrogen output in the subject’s urine, fecal matter and dermal loss, a net nitrogen balance was calculated. This figure reveals how much of the dietary protein was utilized by the body.
Because the methodology of the nitrogen balance is only valid when carried out in an accurate manner, numerous precautions were taken to ensure the data was valid. All told, this study used 8 separate actions, as outlined in the study’s methodology.
The paper further goes on to elaborate on how to determine the paths that the protein can take in the body. When a protein is digested (enzymatically hydrolyzed during the digestive tract), its constituent amino acids are released and absorbed in the small intestine. From here they will either follow one of the two metabolic pathways:
- Anabolic pathway , in which the amino acids act as precursors of body protein synthesis (primary function of amino acids) without providing either energy nor nitrogen catabolites.
- Catabolic pathway , in which the amino acids are deaminated, which means that their amino groups (NH2) are separated from their carboxylic groups (COOH) providing energy and originating energy and nitrogen catabolites (secondary function of amino acids).
Over each of the corresponding four-week periods of the study, the urine and feces of each subject was collected daily to determine the nitrogen content. A specific calculation was also made to determine any nitrogen output through the skin, since it is a minor pathway of detoxification.
Compiling this information with the positive or negative nitrogen balance, the Amino Acid Utilization was then calculated, which is described in detail in the study’s methodology.
During the intake of PA, there were no side effects, nor any adverse effects on blood parameters.
The conclusion of this study, confirmed that the formula now in PA, is the ideal amino acid formula for human nutrition. This formula is the only one that can give the body an Amino Acid Utilization (AAU) of 99%, meaning that 99% gets utilized by the body to build or repair body proteins and that only 1% generated energy and nitrogen catabolites. It also found that this formula provided less than half of a calorie per gram of amino acids.
From this information to hand, the authors concluded that this formula can be highly beneficial in the dietary treatment of people with:
- Protein-Energy Malnutrition
- Anorexia
- Bulimia
- Renal insufficiency
- Hepatic insufficiency
- Anemia due to an insufficient erythropoiesis
- Lack of appetite
- Vomiting
- Uncontrollable diarrhea
- Excessive catabolism
- Obesity
More on Amino Acid Utilization, a further explanation and elaboration:
Amino acids are the building blocks of protein. Access to reliable sources of high-quality amino acids and protein is therefore critical to a healthy diet. They permit the growth and maintenance of the 25,000+ proteins encoded within the human genome, as well as other nitrogenous compounds, which together comprise the body’s complex system of structural and functional elements that exchange nitrogen with the environment. In brief, amino acids are the foundation of our physical bodies.
While over 200 amino acids have been described in the literature, only 20 are known to take part in protein synthesis, and thus are called proteinogenic. In nature, all 20 of these amino acids did not appear all at once in our evolution; some of them showed up early while others were added to the genetic code later.
As mentioned, proteinogenic amino acids are used by the body to make protein. For human adults, the following eight amino acids must be obtained via dietary means and, thus, are classified as essential: isoleucine, leucine, lysine, phenylalanine, threonine, tryptophan and valine; histidine is only essential for infants as it is produced by adults. The essential amino acids support and maintain the body’s enzymatic, hormonal, muscular and skeletal systems.
Amino acids are processed by the body via one of two pathways: anabolism— or constructive metabolism, the synthesis of more complex substances from simpler ones—or catabolism— destructive metabolism, the breakdown of more complex substances into simpler ones for energy demands.
When amino acids follow the anabolic pathway they act as precursors of body protein synthesis and form the body’s constituent proteins, which is their main function. In this pathway, no nitrogen catabolites (or metabolic waste) are released. When amino acids follow the catabolic pathway they are deaminated (an amino acid group is removed) and used as energy. In this process they cannot build protein and nitrogen waste is released.
Dietary protein, amino acid requirements and nitrogen balance
Models for dietary protein requirements are centered around the needs of the organism – known as metabolic demands – and the nutritional inputs that will meet those needs – known as efficiency of utilization. The metabolic demand is a measure of our metabolic pathways that consume amino acids. The dietary requirement is the level of protein or amino acids that must be supplied via nutrition in order to meet the metabolic demand and achieve nitrogen equilibrium.
This requirement will typically be greater than the metabolic demand due to factors that affect the efficiency of protein use or net protein utilization. These factors in turn influence the digestibility, the consequent amount of dietary nitrogen lost in feces, and the cellular bioavailability of absorbed amino acids in reference to what the body needs. In short, the dietary requirement compensates for the metabolic inefficiency.
As the intake of protein, amino acids and nitrogen increases, there is a level of consumption that must be met in order for nitrogen balance to be achieved, which is defined as the minimum protein requirement. If the pattern of amino acids consumed is not an exact match to metabolic demands, then nitrogen losses will include nitrogen from amino acids that exceed demand.
How much of each amino acid the body needs varies according to multiple factors, including: body composition, diet, environmental stressors, pathological stressors, physical activity, physiological state, programmed metabolic capacity and sex.
Optimal dietary provision of protein, amino acids and nitrogen to satisfy basal requirements in any individual will only occur when demands are first met for energy and all other nutrients needed for normal cellular and tissue functions. Amino acid metabolism is critically dependent on the amount and quality of food consumed.
Many factors, as noted, affect how well the body metabolizes and utilizes amino acids consumed as part of our diet. High levels of protein intake by athletes, for example, may increase the oxidation of amino acids and, thus, the need for more amino acids.
Smoking and alcohol consumption, too, can each affect demand for increased amino acid consumption, partly since detoxification and excretion of these, and other, chemical agents and xenobiotics can place greater demands on amino acid metabolism. Some medications—for example, acetaminophen—consume amino acids during their detoxification process.
The optimal amino acid profile
In over three decades of research, nutritional science has found is that all living things have a specific composition of amino acids that allows them to achieve maximum protein synthesis. In order for this to take place, however, all eight essential amino acids must be present at the same time and in the exact specific amino acid composition for that organism.
Only then, if there are the eight essential amino acids in the correct reciprocal relationship, the body can build proteins in an optimal manner. In other cases, amino acid utilization (AAU) decreases and, conversely, the load of substances derived from the breakdown of nitrogen (ammonia) increases, which must then be eliminated via the organs of degradation (liver, kidneys). The degradation of amino acids that cannot be used for the synthesis of body proteins yields toxic nitrogen catabolites.
The greater the difference between the optimal ratio and the actual amino acid composition consumed, the lower the protein value, or the net assimilation of the nitrogen of a source of dietary protein.
In essence, AAU has more to do with utilization than efficacy. For example, if one were to consume 10 grams of protein from chicken one would urinate out 6.8 grams of nitrogen, indicating that 68 percent was not utilized for body protein.
PerfectAmino by BodyHealth reaches the highest nutritional value of protein, with a 99% AAU, which signifies that nearly all the amino acids can be used for the synthesis of proteins and, therefore, for cytogenesis (anabolic activity) by the body.
PerfectAmino has virtually no calories because the metabolic degradation of 1% can produce only 1% glucose. People who must maintain a low-carbohydrate regimen can greatly reduce the amount of substances containing glucose, replacing protein food with this amino acid blend.
In addition to athletes, many individuals are often deficient in protein, especially vegans. It is often overlooked that amino acids, together with the good fats, are the main producers of hormones, and a hormonal unbalance is very often connected to low quality protein.
Regarding protein, only 18% or less of whey and soy protein is utilized by the body with 83% leaving as waste. Protein from such sources as meat, fish and poultry are absorbed at 32%, with 68% wasted. Eggs are utilized at 48%, with 52% converted to waste.
As noted, PerfectAmino is 99% utilized by the body, leaving only 1% as waste. In addition, this formula does not require catalytic enzymes and is available for body use in blood very quickly.
Active individuals often require higher doses of amino acid supplements, such as PerfectAmino, to provide their bodies adequate building blocks for protein synthesis—critical for healing, muscle recovery and stamina.
NOTE: This is an informational webpage regarding this subject and references the 1998 European study that was not, however, conducted or written by the authors of this webpage.
References
Akram, Asif HM, Uzair M, et al. Amino acids: A review article. J Med Plant Res. 2011; 5(17):3997-4000.
Bilsborough S, Mann N. A review of issues of dietary protein intake in humans. Int J Sport Nutr Exerc Metab. 2006;16(2):129-152.
Boisen S, Hvelplund T, Weisbjerg MR. Ideal amino acid profiles as a basis for feed protein evaluation. Live Prod Sci. 2000;64:239-251.
Brestensky M, Nitrayova S, Patras P, et al. Branched chain amino acids and their importance in nutrition. J Microbiol Biotechnol Food Sci. 2015;5(2):197-202.
Brunton JA, Shoveller AK, Pencharz PB, Ball RO. The indicator amino acid oxidation method identified limiting amino acids in two parenteral nutrition solutions in neonatal piglets. J Nutr. 2007;137:1253-1259.
Cuthbertson D, Smith K, Babraj J, et al. Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle. FASEB J. 2005;19(3):422-424.
Gilani GS, Cockell KA, Sepehr E. Effects of antinutritional factors on protein digestibility and amino acid availability in foods. J AOAC Int. 2005;88(3):967-987.
Helms ER, Zinn C, Rowlands DS, Brown SR. A systematic review of dietary protein during caloric restriction in resistance trained lean athletes: a case for higher intakes. Int J Sport Nutr Exerc Metab. 2014;24(2):127-138.
Kerksick CM, Rasmussen CJ, Lancaster SL, et al. The effects of protein and amino acid supplementation on performance and training adaptations during ten weeks of resistance training. J Strength Cond Res. 2006;20(3):643-653.
Krehbiel CR, Matthews JC. Absorption of amino acids and peptides. In: Amino Acids in Animal Nutrition. CAB International. 2003.
Li P, Yin YL, Li D, et al. Amino acids and immune function. Br J Nutr. 2007;98(2):237-252.
Otter DE. Standardised methods for amino acid analysis in foods. Br J Nutr. 2012;108 (Suppl 2):S230-S237.
Pasiakos SM. Exercise and amino acid anabolic cell signaling and the regulation of skeletal muscle mass. Nutrients. 4(7):740-758.
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